New Clinical Study Reveals Actiserine Delivers Over 3X the Absorption of Conventional Phosphatidylserine
April 8th, 2025 — SD Head USA, in partnership with Shankar Nutricon, proudly announces the results of a breakthrough clinical study confirming the superior bioavailability of Actiserine, a next-generation brain health ingredient that redefines the standard for Phosphatidylserine (PS) supplementation.
This exciting innovation will be unveiled at SupplySide Connect New Jersey, where SD Head USA and Shankar Nutricon will showcase the clinical data and offer a first look at how Actiserine is transforming cognitive health solutions. SD Head USA is the exclusive distributor of Actiserine in North America, bringing this clinically proven innovation directly to partners and consumers across the region. Attendees are invited to visit the SD Head exhibition to explore the science and formulation opportunities behind this new gold standard in PS delivery.
Formulated with a proprietary blend of PS, Catechins, and Arabinose, Actiserine delivers significantly higher levels of circulating PS compared to conventional formulations—unlocking enhanced cognitive benefits for users.
Clinically Proven Performance
In a double-blind, randomized, crossover study involving 30 healthy adults, Actiserine demonstrated:
- 3.4X higher total absorption (AUC₀–t)
- 2.8X higher peak concentration (Cmax)
- No adverse events reported
Each participant received both Actiserine and conventional PS in separate phases under fasting conditions. Key pharmacokinetic measurements showed:
- Cmax: Actiserine – 3.76 µg/mL vs. Conventional PS – 1.34 µg/mL
- AUC₀–48h: Actiserine – 63.65 µg·h/mL vs. 18.75 µg·h/mL
- AUC₀–∞: Actiserine – 73.57 µg·h/mL vs. 19.78 µg·h/mL
- t½ (Half-life): 15.16 hours vs. 7.35 hours
These results validate Actiserine as a safe, highly bioavailable PS formulation that delivers significantly improved nutrient uptake and sustained efficacy.
“With Actiserine, we’ve taken one of the most trusted brain health ingredients and made it dramatically more effective,” said Johnnie Chen, Chief Operating Officer of SD Head USA. “This is more than just improved absorption—it’s a smarter, more efficient way to fuel cognitive performance.”
What Sets Actiserine Apart
Phosphatidylserine is a well-established nutrient that supports memory, focus, mood, and overall brain health. Actiserine amplifies these benefits through a synergistic nanocarrier system that incorporates: Catechins, potent antioxidants that protect brain cells and support healthy cerebral blood flow, as well as a natural sugar called Arabinose that improves nutrient absorption and supports healthy blood glucose levels.
This innovative delivery system ensures greater cognitive support, improved nutrient utilization, and longer-lasting effects compared to standard PS supplements.
A Smarter Solution for Every Brain
Whether you’re a student aiming to boost learning, a professional seeking sharper focus, or an older adult looking to support cognitive wellbeing, Actiserine delivers the benefits of PS in a form that works harder—and smarter—for your brain.
About
SD Head USA is one of the leading enterprises in cellulose ethers and vegetarian (HPMC) hard empty capsules. We strive each and every day to serve our customers with top-quality products. With a combined surface area of 300,000 square meters, annual capacities of 85,000 metric tons of cellulose ethers and 300 billion units of HPMC capsules, and more than 1,600 employees, we are among the largest operations in the world. Committed to innovation and customer success, SD Head USA partners with globally recognized manufacturers to bring scientifically validated, sustainable ingredients to market.
Founded in 1984, Shankar Nutricon is a global leader in natural lecithin and phospholipid ingredients. Headquartered in Indore, India, the company transforms by-products from the edible oil industry into high-value, sustainable solutions for food, nutrition, and health applications. With advanced manufacturing, strict quality standards, and a strong commitment to sustainability and social responsibility, Shankar Nutricon is shaping a healthier, more natural future.
Contact SD Head USA
To learn more Actiserine, reach out and get in touch with a representative from SD Head USA, the exclusive distributor of Actiserine in the United States and Canada.